BRD-K22134346_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K22134346_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
C8ORF4 chromosome 8 open reading frame 4
CCNB2 cyclin B2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DUSP5 dual specificity phosphatase 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
MSMO1 methylsterol monooxygenase 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
TMEM100 transmembrane protein 100
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
APOD apolipoprotein D
BEX1 brain expressed, X-linked 1
CD24 CD24 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNPY3 canopy FGF signaling regulator 3
COL2A1 collagen, type II, alpha 1
COL9A3 collagen, type IX, alpha 3
CXCL14 chemokine (C-X-C motif) ligand 14
ELN elastin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FABP7 fatty acid binding protein 7, brain
FCGBP Fc fragment of IgG binding protein
FRS2 fibroblast growth factor receptor substrate 2
RBP4 retinol binding protein 4, plasma
RGS5 regulator of G-protein signaling 5
S100A7 S100 calcium binding protein A7
SPRY2 sprouty homolog 2 (Drosophila)
TUBB2B tubulin, beta 2B class IIb