BRD-K22010301_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K22010301_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
BAG3 BCL2-associated athanogene 3
CBR3 carbonyl reductase 3
CLU clusterin
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
LAPTM4B lysosomal protein transmembrane 4 beta
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP3 nuclear receptor interacting protein 3
OAT ornithine aminotransferase
PGD phosphogluconate dehydrogenase
PHTF2 putative homeodomain transcription factor 2
RAP1GAP RAP1 GTPase activating protein
SFN stratifin
SQLE squalene epoxidase
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
CDC20 cell division cycle 20
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTGF connective tissue growth factor
EDNRA endothelin receptor type A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EREG epiregulin
FGFR2 fibroblast growth factor receptor 2
FOXG1 forkhead box G1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
MDFIC MyoD family inhibitor domain containing
MGP matrix Gla protein
RAB25 RAB25, member RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RRAGD Ras-related GTP binding D
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCEL sciellin
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SFRP1 secreted frizzled-related protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TRIM2 tripartite motif containing 2
VSNL1 visinin-like 1
WNT5A wingless-type MMTV integration site family, member 5A