BRD-K21906513_UNC669_HEPG2_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K21906513_UNC669_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM9 ADAM metallopeptidase domain 9
AKAP12 A kinase (PRKA) anchor protein 12
ANXA10 annexin A10
ARHGAP29 Rho GTPase activating protein 29
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BST2 bone marrow stromal cell antigen 2
C10ORF10 chromosome 10 open reading frame 10
CD24 CD24 molecule
CKS1B CDC28 protein kinase regulatory subunit 1B
CXADR coxsackie virus and adenovirus receptor
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DEFB1 defensin, beta 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
EPHA3 EPH receptor A3
FGFR2 fibroblast growth factor receptor 2
FRZB frizzled-related protein
GAGE3 G antigen 3
HBE1 hemoglobin, epsilon 1
HEATR1 HEAT repeat containing 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KRT18 keratin 18, type I
LAMA3 laminin, alpha 3
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MCAM melanoma cell adhesion molecule
METTL7A methyltransferase like 7A
MMP10 matrix metallopeptidase 10
MT1E metallothionein 1E
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NEBL nebulette
NELL2 NEL-like 2 (chicken)
NFIB nuclear factor I/B
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PSCA prostate stem cell antigen
PSD3 pleckstrin and Sec7 domain containing 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PXDN peroxidasin
SDC2 syndecan 2
SEPT10 septin 10
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
TES testin LIM domain protein
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast)
TMEM100 transmembrane protein 100
TRIM2 tripartite motif containing 2
WBP5 WW domain binding protein 5
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASRGL1 asparaginase like 1
ATP8B4 ATPase, class I, type 8B, member 4
BAD BCL2-associated agonist of cell death
BASP1 brain abundant, membrane attached signal protein 1
BZW2 basic leucine zipper and W2 domains 2
CA12 carbonic anhydrase XII
CCL5 chemokine (C-C motif) ligand 5
CLEC2B C-type lectin domain family 2, member B
CORO1A coronin, actin binding protein, 1A
CRISP3 cysteine-rich secretory protein 3
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
H2AFV H2A histone family, member V
H3F3B H3 histone, family 3B (H3.3B)
HDGFRP3 hepatoma-derived growth factor, related protein 3
HSPA2 heat shock 70kDa protein 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LOXL1 lysyl oxidase-like 1
LRMP lymphoid-restricted membrane protein
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NRCAM neuronal cell adhesion molecule
OXA1L oxidase (cytochrome c) assembly 1-like
PAEP progestagen-associated endometrial protein
RFTN1 raftlin, lipid raft linker 1
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS1 regulator of G-protein signaling 1
TLE4 transducin-like enhancer of split 4
TLK2 tousled-like kinase 2