BRD-K21680192_mitoxantrone_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

63 genes differentially expressed following the BRD-K21680192_mitoxantrone_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CFI complement factor I
CLU clusterin
CNOT4 CCR4-NOT transcription complex, subunit 4
COL11A1 collagen, type XI, alpha 1
DACH1 dachshund family transcription factor 1
DCN decorin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FRMD4B FERM domain containing 4B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNMT histamine N-methyltransferase
HOXA5 homeobox A5
LMO2 LIM domain only 2 (rhombotin-like 1)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SPP1 secreted phosphoprotein 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD2 abhydrolase domain containing 2
ACTN1 actinin, alpha 1
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ANPEP alanyl (membrane) aminopeptidase
BAG2 BCL2-associated athanogene 2
CBR3 carbonyl reductase 3
CCND1 cyclin D1
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
COL6A3 collagen, type VI, alpha 3
CTSB cathepsin B
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
EFNB2 ephrin-B2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
FHL1 four and a half LIM domains 1
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
HMGA1 high mobility group AT-hook 1
IRS2 insulin receptor substrate 2
KRT7 keratin 7, type II
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NBPF10 neuroblastoma breakpoint family, member 10
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPY neuropeptide Y
PAN2 PAN2 poly(A) specific ribonuclease subunit
POPDC3 popeye domain containing 3
PXDN peroxidasin
S100P S100 calcium binding protein P
SMAD3 SMAD family member 3
SMC1A structural maintenance of chromosomes 1A
SPRY2 sprouty homolog 2 (Drosophila)
SYT1 synaptotagmin I
TNC tenascin C
TPM2 tropomyosin 2 (beta)
XIST X inactive specific transcript (non-protein coding)