BRD-K21672423_7611062_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

20 genes differentially expressed following the BRD-K21672423_7611062_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
GCLC glutamate-cysteine ligase, catalytic subunit
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
MSMB microseminoprotein, beta-
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
CA2 carbonic anhydrase II
CD44 CD44 molecule (Indian blood group)
CXCL12 chemokine (C-X-C motif) ligand 12
DKK1 dickkopf WNT signaling pathway inhibitor 1
IGFBP5 insulin-like growth factor binding protein 5
LYZ lysozyme
PXDN peroxidasin
SMC1A structural maintenance of chromosomes 1A
SPINT1 serine peptidase inhibitor, Kunitz type 1
STC1 stanniocalcin 1
TOR1A torsin family 1, member A (torsin A)