BRD-K21520694_Sulfacetamide sodic hydrate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K21520694_Sulfacetamide sodic hydrate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIPOQ adiponectin, C1Q and collagen domain containing
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
CHPT1 choline phosphotransferase 1
CTTN cortactin
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FOLR1 folate receptor 1 (adult)
FOXC1 forkhead box C1
GMDS GDP-mannose 4,6-dehydratase
GSN gelsolin
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXC6 homeobox C6
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
ITGA6 integrin, alpha 6
KIAA0100 KIAA0100
KYNU kynureninase
LIMS1 LIM and senescent cell antigen-like domains 1
LTF lactotransferrin
MARCKSL1 MARCKS-like 1
MTUS1 microtubule associated tumor suppressor 1
MYO6 myosin VI
NUTF2 nuclear transport factor 2
PDGFRL platelet-derived growth factor receptor-like
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PSPH phosphoserine phosphatase
RNASET2 ribonuclease T2
S100P S100 calcium binding protein P
SCML1 sex comb on midleg-like 1 (Drosophila)
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TM4SF1 transmembrane 4 L six family member 1
UFM1 ubiquitin-fold modifier 1

decreased expression

Symbol Name
AREG amphiregulin
BEX1 brain expressed, X-linked 1
C3ORF14 chromosome 3 open reading frame 14
C4BPA complement component 4 binding protein, alpha
CA2 carbonic anhydrase II
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CD40 CD40 molecule, TNF receptor superfamily member 5
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPA3 carboxypeptidase A3 (mast cell)
CTNND1 catenin (cadherin-associated protein), delta 1
EPAS1 endothelial PAS domain protein 1
FGG fibrinogen gamma chain
FN1 fibronectin 1
FRZB frizzled-related protein
GJA1 gap junction protein, alpha 1, 43kDa
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
IGFBP7 insulin-like growth factor binding protein 7
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KRT15 keratin 15, type I
MPC2 mitochondrial pyruvate carrier 2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
NDNF neuron-derived neurotrophic factor
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
RND3 Rho family GTPase 3
RTN1 reticulon 1
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SFTPC surfactant protein C
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SNAI2 snail family zinc finger 2
SYT1 synaptotagmin I
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM176B transmembrane protein 176B
TPBG trophoblast glycoprotein
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)