BRD-K21165668_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-K21165668_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CKB creatine kinase, brain
CORO1A coronin, actin binding protein, 1A
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
FRY furry homolog (Drosophila)
GPNMB glycoprotein (transmembrane) nmb
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
PLN phospholamban
SQLE squalene epoxidase
TMEM47 transmembrane protein 47
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
CYR61 cysteine-rich, angiogenic inducer, 61
H2AFY H2A histone family, member Y
NNMT nicotinamide N-methyltransferase
PTRF polymerase I and transcript release factor
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRGN serglycin
TMCO1 transmembrane and coiled-coil domains 1