BRD-K21064560_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K21064560_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA12 carbonic anhydrase XII
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLEC2B C-type lectin domain family 2, member B
CYTIP cytohesin 1 interacting protein
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
EML3 echinoderm microtubule associated protein like 3
EVI2A ecotropic viral integration site 2A
F13A1 coagulation factor XIII, A1 polypeptide
FTH1 ferritin, heavy polypeptide 1
GPER1 G protein-coupled estrogen receptor 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
ITM2A integral membrane protein 2A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM3A lysine (K)-specific demethylase 3A
LGALS8 lectin, galactoside-binding, soluble, 8
LIMCH1 LIM and calponin homology domains 1
LRMP lymphoid-restricted membrane protein
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
MUC16 mucin 16, cell surface associated
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NPTX2 neuronal pentraxin II
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDE10A phosphodiesterase 10A
PRUNE prune exopolyphosphatase
REEP5 receptor accessory protein 5
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB2A1 secretoglobin, family 2A, member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STC2 stanniocalcin 2
SUSD4 sushi domain containing 4
TCF4 transcription factor 4
TPD52L1 tumor protein D52-like 1
WDR7 WD repeat domain 7
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
C8ORF4 chromosome 8 open reading frame 4
CD59 CD59 molecule, complement regulatory protein
CDCA4 cell division cycle associated 4
CXCL14 chemokine (C-X-C motif) ligand 14
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
GPX1 glutathione peroxidase 1
GSN gelsolin
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
JAG1 jagged 1
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
NFIB nuclear factor I/B
PDLIM1 PDZ and LIM domain 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRMT1 protein arginine methyltransferase 1
SDC4 syndecan 4
THBS1 thrombospondin 1
TOR1A torsin family 1, member A (torsin A)
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
UBE2E3 ubiquitin-conjugating enzyme E2E 3
UBE2S ubiquitin-conjugating enzyme E2S