BRD-K21025364_NVP-TAE226_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K21025364_NVP-TAE226_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOD apolipoprotein D
ATP9A ATPase, class II, type 9A
BEX1 brain expressed, X-linked 1
C1RL complement component 1, r subcomponent-like
CD69 CD69 molecule
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
ERBB3 erb-b2 receptor tyrosine kinase 3
FBLN1 fibulin 1
FCGBP Fc fragment of IgG binding protein
FOXN3 forkhead box N3
FOXO4 forkhead box O4
FZD2 frizzled class receptor 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GSN gelsolin
IFI27 interferon, alpha-inducible protein 27
KRAS Kirsten rat sarcoma viral oncogene homolog
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MFAP5 microfibrillar associated protein 5
MVP major vault protein
NUPR1 nuclear protein, transcriptional regulator, 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCP4 Purkinje cell protein 4
PEG3 paternally expressed 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAC8 placenta-specific 8
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SESN1 sestrin 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TFF3 trefoil factor 3 (intestinal)
TST thiosulfate sulfurtransferase (rhodanese)
TUBA1A tubulin, alpha 1a
VGLL4 vestigial-like family member 4
WDTC1 WD and tetratricopeptide repeats 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ACSL1 acyl-CoA synthetase long-chain family member 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C6ORF62 chromosome 6 open reading frame 62
CCNA2 cyclin A2
CRIP2 cysteine-rich protein 2
EIF5 eukaryotic translation initiation factor 5
EMP3 epithelial membrane protein 3
FOSL1 FOS-like antigen 1
KLK6 kallikrein-related peptidase 6
MAL mal, T-cell differentiation protein
MARCO macrophage receptor with collagenous structure
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLK1 polo-like kinase 1
RPL38 ribosomal protein L38
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A9 S100 calcium binding protein A9
SCEL sciellin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THBS1 thrombospondin 1
TREM1 triggering receptor expressed on myeloid cells 1
VDAC1 voltage-dependent anion channel 1