BRD-K20755323_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-K20755323_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHIC2 cysteine-rich hydrophobic domain 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
F11R F11 receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSL1 FOS-like antigen 1
FST follistatin
FTH1 ferritin, heavy polypeptide 1
GBP2 guanylate binding protein 2, interferon-inducible
GCLM glutamate-cysteine ligase, modifier subunit
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HMOX1 heme oxygenase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI16 interferon, gamma-inducible protein 16
INHBB inhibin, beta B
KDM3A lysine (K)-specific demethylase 3A
KLF9 Kruppel-like factor 9
KRT19 keratin 19, type I
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MAGEA3 melanoma antigen family A3
MAGEA4 melanoma antigen family A4
MAGEA6 melanoma antigen family A6
MAP1B microtubule-associated protein 1B
MT1G metallothionein 1G
MT1H metallothionein 1H
NQO1 NAD(P)H dehydrogenase, quinone 1
PDGFA platelet-derived growth factor alpha polypeptide
PHLDA2 pleckstrin homology-like domain, family A, member 2
RND3 Rho family GTPase 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIK1 salt-inducible kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SQSTM1 sequestosome 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGIF1 TGFB-induced factor homeobox 1
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FHL1 four and a half LIM domains 1
FLRT3 fibronectin leucine rich transmembrane protein 3
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GJA1 gap junction protein, alpha 1, 43kDa
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H1FX H1 histone family, member X
HOXC6 homeobox C6
HSPB8 heat shock 22kDa protein 8
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KIF20A kinesin family member 20A
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDZK1 PDZ domain containing 1
PDZK1IP1 PDZK1 interacting protein 1
PLK1 polo-like kinase 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
TFPI2 tissue factor pathway inhibitor 2
THAP11 THAP domain containing 11
TMSB15A thymosin beta 15a
TPPP3 tubulin polymerization-promoting protein family member 3
TRIL TLR4 interactor with leucine-rich repeats
TSPAN13 tetraspanin 13
ZDHHC11 zinc finger, DHHC-type containing 11