BRD-K20755323_-666_A375_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K20755323_-666_A375_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
CA2 carbonic anhydrase II
CANX calnexin
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
G6PD glucose-6-phosphate dehydrogenase
GARS glycyl-tRNA synthetase
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
MANF mesencephalic astrocyte-derived neurotrophic factor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NDRG1 N-myc downstream regulated 1
PDIA4 protein disulfide isomerase family A, member 4
PLIN2 perilipin 2
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAD9A RAD9 homolog A (S. pombe)
RGCC regulator of cell cycle
SDF2L1 stromal cell-derived factor 2-like 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERP1 stress-associated endoplasmic reticulum protein 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
XBP1 X-box binding protein 1

decreased expression

Symbol Name
AURKA aurora kinase A
CCND1 cyclin D1
CCNF cyclin F
HIST1H2BG histone cluster 1, H2bg
PBK PDZ binding kinase
RPS11 ribosomal protein S11
TOP2A topoisomerase (DNA) II alpha 170kDa