BRD-K20696416_NVP-AEW541_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K20696416_NVP-AEW541_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ALDOC aldolase C, fructose-bisphosphate
CAST calpastatin
CD24 CD24 molecule
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DAPK1 death-associated protein kinase 1
DEFB1 defensin, beta 1
EGFR epidermal growth factor receptor
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
GAS6 growth arrest-specific 6
GRN granulin
HBB hemoglobin, beta
HNMT histamine N-methyltransferase
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IRS2 insulin receptor substrate 2
KYNU kynureninase
LBH limb bud and heart development
LITAF lipopolysaccharide-induced TNF factor
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKS myristoylated alanine-rich protein kinase C substrate
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PBX1 pre-B-cell leukemia homeobox 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS5 regulator of G-protein signaling 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB1 SATB homeobox 1
SCGB1D2 secretoglobin, family 1D, member 2
SDC4 syndecan 4
SEPP1 selenoprotein P, plasma, 1
SOX4 SRY (sex determining region Y)-box 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TFF1 trefoil factor 1
TM4SF4 transmembrane 4 L six family member 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TXNIP thioredoxin interacting protein
VAT1 vesicle amine transport 1
VNN1 vanin 1

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AMD1 adenosylmethionine decarboxylase 1
BAG3 BCL2-associated athanogene 3
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CCNB2 cyclin B2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL3A1 collagen, type III, alpha 1
CSRP2 cysteine and glycine-rich protein 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
G0S2 G0/G1 switch 2
JMJD6 jumonji domain containing 6
KRT13 keratin 13, type I
LTF lactotransferrin
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP9 matrix metallopeptidase 9
NUP98 nucleoporin 98kDa
PLBD1 phospholipase B domain containing 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PSAT1 phosphoserine aminotransferase 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
SPINK5 serine peptidase inhibitor, Kazal type 5
TSPYL5 TSPY-like 5