BRD-K20526256_HG-14-10-04_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K20526256_HG-14-10-04_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AQP1 aquaporin 1 (Colton blood group)
BAD BCL2-associated agonist of cell death
CAPN1 calpain 1, (mu/I) large subunit
CCDC92 coiled-coil domain containing 92
CLEC2B C-type lectin domain family 2, member B
CLU clusterin
COL3A1 collagen, type III, alpha 1
CPD carboxypeptidase D
CRISP3 cysteine-rich secretory protein 3
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DHCR24 24-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
GJA1 gap junction protein, alpha 1, 43kDa
GPATCH8 G patch domain containing 8
HBB hemoglobin, beta
HDAC6 histone deacetylase 6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDS iduronate 2-sulfatase
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
JUP junction plakoglobin
LCN2 lipocalin 2
LINC00341 long intergenic non-protein coding RNA 341
MTUS1 microtubule associated tumor suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDE4B phosphodiesterase 4B, cAMP-specific
PDZK1IP1 PDZK1 interacting protein 1
RAP1GAP2 RAP1 GTPase activating protein 2
RGS1 regulator of G-protein signaling 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SYT1 synaptotagmin I
TCTA T-cell leukemia translocation altered
TPP1 tripeptidyl peptidase I
TRIM16 tripartite motif containing 16
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ATAD2 ATPase family, AAA domain containing 2
CAPN6 calpain 6
CCNE2 cyclin E2
CDC20 cell division cycle 20
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
DFNA5 deafness, autosomal dominant 5
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FOSL1 FOS-like antigen 1
FXYD6 FXYD domain containing ion transport regulator 6
GATA3 GATA binding protein 3
GPM6B glycoprotein M6B
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
KIF14 kinesin family member 14
LAMC2 laminin, gamma 2
LPXN leupaxin
MGLL monoglyceride lipase
MTERF3 mitochondrial transcription termination factor 3
NEB nebulin
NFIB nuclear factor I/B
NTS neurotensin
PDLIM1 PDZ and LIM domain 1
PDLIM4 PDZ and LIM domain 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PKP1 plakophilin 1
PLAT plasminogen activator, tissue
PLK1 polo-like kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POSTN periostin, osteoblast specific factor
PURA purine-rich element binding protein A
RAD51C RAD51 paralog C
RBM34 RNA binding motif protein 34
RBP1 retinol binding protein 1, cellular
RND3 Rho family GTPase 3
RPS11 ribosomal protein S11
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SYNM synemin, intermediate filament protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TNC tenascin C
VCAN versican