BRD-K20000640_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K20000640_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ARL4C ADP-ribosylation factor-like 4C
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLGN calmegin
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP6 dual specificity phosphatase 6
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPN2 epsin 2
FHL1 four and a half LIM domains 1
GLRX glutaredoxin (thioltransferase)
GPX3 glutathione peroxidase 3
HBB hemoglobin, beta
IFI6 interferon, alpha-inducible protein 6
IL1B interleukin 1, beta
KLF4 Kruppel-like factor 4 (gut)
LDOC1 leucine zipper, down-regulated in cancer 1
MMD monocyte to macrophage differentiation-associated
NRGN neurogranin (protein kinase C substrate, RC3)
OPN3 opsin 3
PF4 platelet factor 4
PHGDH phosphoglycerate dehydrogenase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
S100P S100 calcium binding protein P
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SRGN serglycin
TMX4 thioredoxin-related transmembrane protein 4
TSPAN13 tetraspanin 13
UBE2L6 ubiquitin-conjugating enzyme E2L 6

decreased expression

Symbol Name
CDC25A cell division cycle 25A
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GINS2 GINS complex subunit 2 (Psf2 homolog)
KDM5D lysine (K)-specific demethylase 5D
LRRC15 leucine rich repeat containing 15
LTF lactotransferrin
RPS4Y1 ribosomal protein S4, Y-linked 1
SMAD1 SMAD family member 1
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)