BRD-K19724398_-666_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

140 genes differentially expressed following the BRD-K19724398_-666_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
AIM1 absent in melanoma 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOA2 apolipoprotein A-II
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATF5 activating transcription factor 5
ATP10D ATPase, class V, type 10D
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BTG1 B-cell translocation gene 1, anti-proliferative
C3ORF14 chromosome 3 open reading frame 14
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCP110 centriolar coiled coil protein 110kDa
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLDN10 claudin 10
CPM carboxypeptidase M
CRISP3 cysteine-rich secretory protein 3
CSNK2A2 casein kinase 2, alpha prime polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DLK1 delta-like 1 homolog (Drosophila)
DUSP10 dual specificity phosphatase 10
DUSP6 dual specificity phosphatase 6
FAM117A family with sequence similarity 117, member A
FGFR3 fibroblast growth factor receptor 3
FNBP1 formin binding protein 1
FOXO1 forkhead box O1
FZD7 frizzled class receptor 7
G0S2 G0/G1 switch 2
GAL galanin/GMAP prepropeptide
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
GSN gelsolin
H3F3B H3 histone, family 3B (H3.3B)
HECA headcase homolog (Drosophila)
HES1 hes family bHLH transcription factor 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IER5 immediate early response 5
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPP1 inositol polyphosphate-1-phosphatase
INSIG1 insulin induced gene 1
INSR insulin receptor
IRS2 insulin receptor substrate 2
KDM3A lysine (K)-specific demethylase 3A
KLF11 Kruppel-like factor 11
KRT5 keratin 5, type II
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP7 microtubule-associated protein 7
MAPK13 mitogen-activated protein kinase 13
MARK4 MAP/microtubule affinity-regulating kinase 4
MDK midkine (neurite growth-promoting factor 2)
MOAP1 modulator of apoptosis 1
MOSPD1 motile sperm domain containing 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO6 myosin VI
NDRG1 N-myc downstream regulated 1
OPTN optineurin
PBX3 pre-B-cell leukemia homeobox 3
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFA platelet-derived growth factor alpha polypeptide
PEG10 paternally expressed 10
PELI1 pellino E3 ubiquitin protein ligase 1
PRKCD protein kinase C, delta
RCAN1 regulator of calcineurin 1
RGCC regulator of cell cycle
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RORA RAR-related orphan receptor A
S100A7 S100 calcium binding protein A7
SDC2 syndecan 2
SESN1 sestrin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPRY2 sprouty homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
SSBP2 single-stranded DNA binding protein 2
STC1 stanniocalcin 1
TACSTD2 tumor-associated calcium signal transducer 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TOB1 transducer of ERBB2, 1
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
YPEL5 yippee-like 5 (Drosophila)
ZDHHC11 zinc finger, DHHC-type containing 11
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BOP1 block of proliferation 1
CCL2 chemokine (C-C motif) ligand 2
CDCA4 cell division cycle associated 4
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
CREB1 cAMP responsive element binding protein 1
DICER1 dicer 1, ribonuclease type III
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ENO1 enolase 1, (alpha)
EPHB2 EPH receptor B2
GABPB1 GA binding protein transcription factor, beta subunit 1
GBP1 guanylate binding protein 1, interferon-inducible
GPX2 glutathione peroxidase 2
HN1L hematological and neurological expressed 1-like
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFRD2 interferon-related developmental regulator 2
IPO7 importin 7
JCHAIN joining chain of multimeric IgA and IgM
KIAA0101 KIAA0101
LDOC1 leucine zipper, down-regulated in cancer 1
LYZ lysozyme
MAT2A methionine adenosyltransferase II, alpha
MINA MYC induced nuclear antigen
MLPH melanophilin
MRPL15 mitochondrial ribosomal protein L15
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5C myosin VC
NBN nibrin
NEFL neurofilament, light polypeptide
NLE1 notchless homolog 1 (Drosophila)
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRIP1 nuclear receptor interacting protein 1
NUP62 nucleoporin 62kDa
PARP2 poly (ADP-ribose) polymerase 2
PON2 paraoxonase 2
PRMT3 protein arginine methyltransferase 3
RPIA ribose 5-phosphate isomerase A
SRGN serglycin
STC2 stanniocalcin 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM230 transmembrane protein 230
TNC tenascin C
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UCK2 uridine-cytidine kinase 2
ZFP36L1 ZFP36 ring finger protein-like 1