BRD-K19687926_HY-50898_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K19687926_HY-50898_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOH apolipoprotein H (beta-2-glycoprotein I)
ARL3 ADP-ribosylation factor-like 3
COBLL1 cordon-bleu WH2 repeat protein-like 1
DDHD2 DDHD domain containing 2
FGB fibrinogen beta chain
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
FTH1 ferritin, heavy polypeptide 1
GLUL glutamate-ammonia ligase
GNAS GNAS complex locus
HBB hemoglobin, beta
METRN meteorin, glial cell differentiation regulator
MYB v-myb avian myeloblastosis viral oncogene homolog
MYO6 myosin VI
NME5 NME/NM23 family member 5
NUPR1 nuclear protein, transcriptional regulator, 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG3 paternally expressed 3
PLEK pleckstrin
PSIP1 PC4 and SFRS1 interacting protein 1
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNC1 troponin C type 1 (slow)
TNS3 tensin 3
VAV3 vav 3 guanine nucleotide exchange factor
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOA aldolase A, fructose-bisphosphate
CANT1 calcium activated nucleotidase 1
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL3 chemokine (C-X-C motif) ligand 3
DCLK1 doublecortin-like kinase 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
FOSL1 FOS-like antigen 1
GEM GTP binding protein overexpressed in skeletal muscle
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
JUN jun proto-oncogene
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIF leukemia inhibitory factor
LMO3 LIM domain only 3 (rhombotin-like 2)
OLFM4 olfactomedin 4
PDE4D phosphodiesterase 4D, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PMP22 peripheral myelin protein 22
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
REG1A regenerating islet-derived 1 alpha
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P
SCUBE2 signal peptide, CUB domain, EGF-like 2
SOX9 SRY (sex determining region Y)-box 9
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STC1 stanniocalcin 1
SYNJ2 synaptojanin 2
SYNM synemin, intermediate filament protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THAP11 THAP domain containing 11
TMEM158 transmembrane protein 158 (gene/pseudogene)
TPSAB1 tryptase alpha/beta 1
VEGFA vascular endothelial growth factor A