BRD-K19624190_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K19624190_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP5 dual specificity phosphatase 5
FKBP11 FK506 binding protein 11, 19 kDa
FOXD1 forkhead box D1
GARS glycyl-tRNA synthetase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
ISG20 interferon stimulated exonuclease gene 20kDa
KLF4 Kruppel-like factor 4 (gut)
MARS methionyl-tRNA synthetase
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPAP2B phosphatidic acid phosphatase type 2B
SCGB1D2 secretoglobin, family 1D, member 2
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TFF3 trefoil factor 3 (intestinal)
VTCN1 V-set domain containing T cell activation inhibitor 1
WARS tryptophanyl-tRNA synthetase
WDR45 WD repeat domain 45
XBP1 X-box binding protein 1
YARS tyrosyl-tRNA synthetase

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AURKA aurora kinase A
B3GNT1
CCNF cyclin F
DPYSL3 dihydropyrimidinase-like 3
GAS2L1 growth arrest-specific 2 like 1
GPM6A glycoprotein M6A
JADE2 jade family PHD finger 2
KARS lysyl-tRNA synthetase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MXRA7 matrix-remodelling associated 7
PCDH9 protocadherin 9
PCNA proliferating cell nuclear antigen
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
S100A10 S100 calcium binding protein A10
SORBS1 sorbin and SH3 domain containing 1
STK39 serine threonine kinase 39
SYNM synemin, intermediate filament protein
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
ZDHHC3 zinc finger, DHHC-type containing 3