BRD-K19540840_saracatinib_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K19540840_saracatinib_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CHMP6 charged multivesicular body protein 6
HBB hemoglobin, beta
HIST1H2AC histone cluster 1, H2ac
LCN2 lipocalin 2
LY96 lymphocyte antigen 96
MPO myeloperoxidase
PDZK1IP1 PDZK1 interacting protein 1
PXDN peroxidasin
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TXNIP thioredoxin interacting protein
VCAN versican
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
BHLHE40 basic helix-loop-helix family, member e40
CADM1 cell adhesion molecule 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTGF connective tissue growth factor
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR3 early growth response 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
GDF15 growth differentiation factor 15
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
KDM5D lysine (K)-specific demethylase 5D
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYC v-myc avian myelocytomatosis viral oncogene homolog
NELL2 NEL-like 2 (chicken)
NR4A3 nuclear receptor subfamily 4, group A, member 3
PEG10 paternally expressed 10
PER2 period circadian clock 2
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
RPS4Y1 ribosomal protein S4, Y-linked 1
SH3BP4 SH3-domain binding protein 4
SIK1 salt-inducible kinase 1
TGFBI transforming growth factor, beta-induced, 68kDa