BRD-K19540840_saracatinib_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

69 genes differentially expressed following the BRD-K19540840_saracatinib_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AGR2 anterior gradient 2
ANOS1 anosmin 1
AQP3 aquaporin 3 (Gill blood group)
CA2 carbonic anhydrase II
CD36 CD36 molecule (thrombospondin receptor)
CLCA2 chloride channel accessory 2
CPA3 carboxypeptidase A3 (mast cell)
DHCR24 24-dehydrocholesterol reductase
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLK1 delta-like 1 homolog (Drosophila)
EGR1 early growth response 1
ESR1 estrogen receptor 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FGFR3 fibroblast growth factor receptor 3
FXYD3 FXYD domain containing ion transport regulator 3
GSTA1 glutathione S-transferase alpha 1
HBB hemoglobin, beta
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JCHAIN joining chain of multimeric IgA and IgM
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT19 keratin 19, type I
KRT5 keratin 5, type II
LPL lipoprotein lipase
LTF lactotransferrin
LY6E lymphocyte antigen 6 complex, locus E
NDNF neuron-derived neurotrophic factor
NELL2 NEL-like 2 (chicken)
NPY1R neuropeptide Y receptor Y1
PENK proenkephalin
PGD phosphogluconate dehydrogenase
PSD3 pleckstrin and Sec7 domain containing 3
PTN pleiotrophin
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TRD T cell receptor delta locus
VDAC1 voltage-dependent anion channel 1
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
EPHB2 EPH receptor B2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
HSPA2 heat shock 70kDa protein 2
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KYNU kynureninase
PTPRF protein tyrosine phosphatase, receptor type, F
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH3BP4 SH3-domain binding protein 4
SPATS2L spermatogenesis associated, serine-rich 2-like
SYNJ2 synaptojanin 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
VAT1 vesicle amine transport 1