BRD-K19309090_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

103 genes differentially expressed following the BRD-K19309090_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
AFP alpha-fetoprotein
AIM1 absent in melanoma 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
APOA2 apolipoprotein A-II
APOB apolipoprotein B
AQP9 aquaporin 9
ARL4C ADP-ribosylation factor-like 4C
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAST calpastatin
CCL20 chemokine (C-C motif) ligand 20
CD52 CD52 molecule
CD9 CD9 molecule
CLCA2 chloride channel accessory 2
CLCA4 chloride channel accessory 4
DPYD dihydropyrimidine dehydrogenase
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAM129A family with sequence similarity 129, member A
FGFR3 fibroblast growth factor receptor 3
FGG fibrinogen gamma chain
GNLY granulysin
HOPX HOP homeobox
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JAG1 jagged 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT5 keratin 5, type II
LPAR6 lysophosphatidic acid receptor 6
LY6D lymphocyte antigen 6 complex, locus D
MAP3K7CL MAP3K7 C-terminal like
MME membrane metallo-endopeptidase
MMP7 matrix metallopeptidase 7
MTSS1 metastasis suppressor 1
MYL2 myosin, light chain 2, regulatory, cardiac, slow
NEB nebulin
OLFM4 olfactomedin 4
ORM1 orosomucoid 1
PDE4A phosphodiesterase 4A, cAMP-specific
PEG10 paternally expressed 10
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POSTN periostin, osteoblast specific factor
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A9 S100 calcium binding protein A9
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPON2 spondin 2, extracellular matrix protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TF transferrin
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TTN titin
VNN1 vanin 1
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
ZIC1 Zic family member 1

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
APOD apolipoprotein D
AQP1 aquaporin 1 (Colton blood group)
ASCL1 achaete-scute family bHLH transcription factor 1
CHGB chromogranin B
COMP cartilage oligomeric matrix protein
CXCL12 chemokine (C-X-C motif) ligand 12
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ESR1 estrogen receptor 1
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
GCH1 GTP cyclohydrolase 1
GPX3 glutathione peroxidase 3
HOXC6 homeobox C6
HSPB8 heat shock 22kDa protein 8
IGFBP4 insulin-like growth factor binding protein 4
IRF8 interferon regulatory factor 8
LAMP5 lysosomal-associated membrane protein family, member 5
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LXN latexin
LY86 lymphocyte antigen 86
MAP7 microtubule-associated protein 7
MAPT microtubule-associated protein tau
MARCKSL1 MARCKS-like 1
MATN2 matrilin 2
NEBL nebulette
NFIB nuclear factor I/B
NNMT nicotinamide N-methyltransferase
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUPL1 nucleoporin like 1
RET ret proto-oncogene
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TPD52L1 tumor protein D52-like 1
TSPAN13 tetraspanin 13
UGCG UDP-glucose ceramide glucosyltransferase
VAT1 vesicle amine transport 1