BRD-K19295594_-666_A375_6.0_h_11.1_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K19295594_-666_A375_6.0_h_11.1_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARMCX3 armadillo repeat containing, X-linked 3
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
DDIT4 DNA-damage-inducible transcript 4
F2RL1 coagulation factor II (thrombin) receptor-like 1
GDF15 growth differentiation factor 15
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KDM3A lysine (K)-specific demethylase 3A
KLF4 Kruppel-like factor 4 (gut)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
NUPR1 nuclear protein, transcriptional regulator, 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHLDA2 pleckstrin homology-like domain, family A, member 2

decreased expression

Symbol Name
AURKA aurora kinase A
C2CD5 C2 calcium-dependent domain containing 5
TOP2A topoisomerase (DNA) II alpha 170kDa