BRD-K19220233_JNK-9L_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K19220233_JNK-9L_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AREG amphiregulin
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFI complement factor I
COL4A5 collagen, type IV, alpha 5
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FJX1 four jointed box 1 (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX1 heme oxygenase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5 immediate early response 5
JUP junction plakoglobin
LDHB lactate dehydrogenase B
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PER2 period circadian clock 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRNP prion protein
PTPRD protein tyrosine phosphatase, receptor type, D
RBP1 retinol binding protein 1, cellular
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SNAP25 synaptosomal-associated protein, 25kDa
SPRY2 sprouty homolog 2 (Drosophila)
TFPI2 tissue factor pathway inhibitor 2
WT1 Wilms tumor 1
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ARMCX2 armadillo repeat containing, X-linked 2
CADM1 cell adhesion molecule 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
HSPA8 heat shock 70kDa protein 8
LUM lumican
LXN latexin
NET1 neuroepithelial cell transforming 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCM1 pericentriolar material 1
PRPS2 phosphoribosyl pyrophosphate synthetase 2
UBE2C ubiquitin-conjugating enzyme E2C
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)