BRD-K19220233_JNK-9L_MCF10A_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K19220233_JNK-9L_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CORO1A coronin, actin binding protein, 1A
ERBB4 erb-b2 receptor tyrosine kinase 4
F3 coagulation factor III (thromboplastin, tissue factor)
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H2BD histone cluster 1, H2bd
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGHMBP2 immunoglobulin mu binding protein 2
IGLL1 immunoglobulin lambda-like polypeptide 1
JAG1 jagged 1
LTB lymphotoxin beta (TNF superfamily, member 3)
MECOM MDS1 and EVI1 complex locus
NPDC1 neural proliferation, differentiation and control, 1
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR2F6 nuclear receptor subfamily 2, group F, member 6
OLFM1 olfactomedin 1
PCDH7 protocadherin 7
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PON3 paraoxonase 3
RTN3 reticulon 3
SCGB2A1 secretoglobin, family 2A, member 1
SPARCL1 SPARC-like 1 (hevin)
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VPREB3 pre-B lymphocyte 3

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ANPEP alanyl (membrane) aminopeptidase
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
C2CD2 C2 calcium-dependent domain containing 2
C3ORF14 chromosome 3 open reading frame 14
CHPT1 choline phosphotransferase 1
CNN3 calponin 3, acidic
CRYAB crystallin, alpha B
CSTA cystatin A (stefin A)
DCN decorin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
DYNLT1 dynein, light chain, Tctex-type 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FBP1 fructose-1,6-bisphosphatase 1
GATA3 GATA binding protein 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GHR growth hormone receptor
GPNMB glycoprotein (transmembrane) nmb
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IFI44 interferon-induced protein 44
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KDM5D lysine (K)-specific demethylase 5D
LMO2 LIM domain only 2 (rhombotin-like 1)
LUM lumican
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEF2C myocyte enhancer factor 2C
NFIB nuclear factor I/B
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PHACTR2 phosphatase and actin regulator 2
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SOD2 superoxide dismutase 2, mitochondrial
SORBS2 sorbin and SH3 domain containing 2
STAR steroidogenic acute regulatory protein
STXBP2 syntaxin binding protein 2
SYNE2 spectrin repeat containing, nuclear envelope 2
TM4SF1 transmembrane 4 L six family member 1
TMEM176B transmembrane protein 176B
TMEM87A transmembrane protein 87A
TUBB6 tubulin, beta 6 class V
USP6NL USP6 N-terminal like