BRD-K19220233_JNK-9L_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K19220233_JNK-9L_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
ANKRD36B ankyrin repeat domain 36B
ANOS1 anosmin 1
APOD apolipoprotein D
ASPN asporin
CAV1 caveolin 1, caveolae protein, 22kDa
CTSK cathepsin K
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GOLGA4 golgin A4
GSN gelsolin
GUSBP3 glucuronidase, beta pseudogene 3
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
LAMP1 lysosomal-associated membrane protein 1
LARS leucyl-tRNA synthetase
LOC100272216 uncharacterized LOC100272216
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MACF1 microtubule-actin crosslinking factor 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MDFIC MyoD family inhibitor domain containing
MEF2C myocyte enhancer factor 2C
NPIPB3 nuclear pore complex interacting protein family, member B3
NUSAP1 nucleolar and spindle associated protein 1
PON3 paraoxonase 3
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPON2 spondin 2, extracellular matrix protein
TCF4 transcription factor 4

decreased expression

Symbol Name
ADM adrenomedullin
ANPEP alanyl (membrane) aminopeptidase
ARID4B AT rich interactive domain 4B (RBP1-like)
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNOT4 CCR4-NOT transcription complex, subunit 4
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GCH1 GTP cyclohydrolase 1
HBB hemoglobin, beta
HES1 hes family bHLH transcription factor 1
IER5 immediate early response 5
LTF lactotransferrin
MARCKSL1 MARCKS-like 1
NFE2L2 nuclear factor, erythroid 2-like 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NXT1 nuclear transport factor 2-like export factor 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PPIF peptidylprolyl isomerase F
RPS4Y1 ribosomal protein S4, Y-linked 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
TBPL1 TBP-like 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGIF1 TGFB-induced factor homeobox 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZDHHC6 zinc finger, DHHC-type containing 6
ZFP36L1 ZFP36 ring finger protein-like 1