BRD-K19181733_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K19181733_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LPIN1 lipin 1
LYZ lysozyme
MBNL2 muscleblind-like splicing regulator 2
MID1IP1 MID1 interacting protein 1
MSMO1 methylsterol monooxygenase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDF2L1 stromal cell-derived factor 2-like 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SQLE squalene epoxidase
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
RGS2 regulator of G-protein signaling 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
TFPI2 tissue factor pathway inhibitor 2