BRD-K19166598_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K19166598_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AGTR1 angiotensin II receptor, type 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CST3 cystatin C
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FOXO3 forkhead box O3
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER3 immediate early response 3
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LGALS2 lectin, galactoside-binding, soluble, 2
LPIN1 lipin 1
LSR lipolysis stimulated lipoprotein receptor
NSDHL NAD(P) dependent steroid dehydrogenase-like
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TUBB2A tubulin, beta 2A class IIa
VEGFA vascular endothelial growth factor A
XBP1 X-box binding protein 1
YARS tyrosyl-tRNA synthetase

decreased expression

Symbol Name
C3 complement component 3
COL3A1 collagen, type III, alpha 1
FABP7 fatty acid binding protein 7, brain
GJA1 gap junction protein, alpha 1, 43kDa
GNAS GNAS complex locus
POSTN periostin, osteoblast specific factor
RELN reelin
VDAC3 voltage-dependent anion channel 3
ZIC1 Zic family member 1