BRD-K19146323_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K19146323_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
C2CD2 C2 calcium-dependent domain containing 2
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLTB clathrin, light chain B
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DHCR7 7-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
FADS1 fatty acid desaturase 1
FKBP10 FK506 binding protein 10, 65 kDa
GRN granulin
H1F0 H1 histone family, member 0
IRS1 insulin receptor substrate 1
JUND jun D proto-oncogene
KLK10 kallikrein-related peptidase 10
LEF1 lymphoid enhancer-binding factor 1
MAP7 microtubule-associated protein 7
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
NAV2 neuron navigator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OLFM4 olfactomedin 4
PI3 peptidase inhibitor 3, skin-derived
PLAU plasminogen activator, urokinase
RAD23B RAD23 homolog B (S. cerevisiae)
SCGB2A2 secretoglobin, family 2A, member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
STC1 stanniocalcin 1
TNC tenascin C
TSC22D3 TSC22 domain family, member 3
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
C1QA complement component 1, q subcomponent, A chain
CA12 carbonic anhydrase XII
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD163 CD163 molecule
CD52 CD52 molecule
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DCN decorin
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FOLR1 folate receptor 1 (adult)
GIMAP6 GTPase, IMAP family member 6
GSTA1 glutathione S-transferase alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFI44L interferon-induced protein 44-like
IL13RA2 interleukin 13 receptor, alpha 2
KRT13 keratin 13, type I
LPAR6 lysophosphatidic acid receptor 6
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
NEB nebulin
PAWR PRKC, apoptosis, WT1, regulator
PDLIM5 PDZ and LIM domain 5
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRUNE2 prune homolog 2 (Drosophila)
RBM3 RNA binding motif (RNP1, RRM) protein 3
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RSL1D1 ribosomal L1 domain containing 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOX11 SRY (sex determining region Y)-box 11
TBCB tubulin folding cofactor B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TUBB2A tubulin, beta 2A class IIa