BRD-K18861610_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

89 genes differentially expressed following the BRD-K18861610_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BMP7 bone morphogenetic protein 7
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CKB creatine kinase, brain
CLCA4 chloride channel accessory 4
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
DUOX2 dual oxidase 2
EGFR epidermal growth factor receptor
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EPN2 epsin 2
FABP4 fatty acid binding protein 4, adipocyte
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
HEBP2 heme binding protein 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
KDM7A lysine (K)-specific demethylase 7A
KRT13 keratin 13, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MMP12 matrix metallopeptidase 12
MTSS1 metastasis suppressor 1
NEBL nebulette
NPIPB3 nuclear pore complex interacting protein family, member B3
PBX1 pre-B-cell leukemia homeobox 1
PERP PERP, TP53 apoptosis effector
PRR15L proline rich 15-like
PTPRC protein tyrosine phosphatase, receptor type, C
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEPT10 septin 10
SPARCL1 SPARC-like 1 (hevin)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPON2 spondin 2, extracellular matrix protein
SPRR3 small proline-rich protein 3
TACC2 transforming, acidic coiled-coil containing protein 2
TPD52 tumor protein D52

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALCAM activated leukocyte cell adhesion molecule
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
BACE2 beta-site APP-cleaving enzyme 2
C8ORF4 chromosome 8 open reading frame 4
CCNE2 cyclin E2
COCH cochlin
CXCL14 chemokine (C-X-C motif) ligand 14
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTH1 cytohesin 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
FGG fibrinogen gamma chain
FOLR1 folate receptor 1 (adult)
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
GPX7 glutathione peroxidase 7
HES1 hes family bHLH transcription factor 1
HOXC6 homeobox C6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6ST interleukin 6 signal transducer
IRS2 insulin receptor substrate 2
KRT14 keratin 14, type I
LEPR leptin receptor
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MMD monocyte to macrophage differentiation-associated
NAAA N-acylethanolamine acid amidase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NQO1 NAD(P)H dehydrogenase, quinone 1
PIR pirin (iron-binding nuclear protein)
PLK2 polo-like kinase 2
PTX3 pentraxin 3, long
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RFK riboflavin kinase
RPS5 ribosomal protein S5
SCML1 sex comb on midleg-like 1 (Drosophila)
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SNX11 sorting nexin 11
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
THBS1 thrombospondin 1
TM2D3 TM2 domain containing 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UFM1 ubiquitin-fold modifier 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor