BRD-K18726304_-666_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K18726304_-666_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ADM adrenomedullin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BAG3 BCL2-associated athanogene 3
BAZ1A bromodomain adjacent to zinc finger domain, 1A
CRIP1 cysteine-rich protein 1 (intestinal)
DUSP6 dual specificity phosphatase 6
E2F2 E2F transcription factor 2
EMX2 empty spiracles homeobox 2
EPS8 epidermal growth factor receptor pathway substrate 8
FOS FBJ murine osteosarcoma viral oncogene homolog
GBE1 glucan (1,4-alpha-), branching enzyme 1
HDDC2 HD domain containing 2
HOXB7 homeobox B7
HSPA1A heat shock 70kDa protein 1A
IRS2 insulin receptor substrate 2
JMJD6 jumonji domain containing 6
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRAME preferentially expressed antigen in melanoma
RCAN1 regulator of calcineurin 1
S100A7 S100 calcium binding protein A7
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SNX11 sorting nexin 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
ANOS1 anosmin 1
AQP1 aquaporin 1 (Colton blood group)
ASS1 argininosuccinate synthase 1
AURKB aurora kinase B
C1ORF116 chromosome 1 open reading frame 116
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CD24 CD24 molecule
CDCA4 cell division cycle associated 4
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRDL1 chordin-like 1
CPE carboxypeptidase E
CSRP1 cysteine and glycine-rich protein 1
CTGF connective tissue growth factor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
DOCK4 dedicator of cytokinesis 4
EIF4A1 eukaryotic translation initiation factor 4A1
FADS2 fatty acid desaturase 2
FCGBP Fc fragment of IgG binding protein
FRZB frizzled-related protein
G0S2 G0/G1 switch 2
GPM6B glycoprotein M6B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IL1B interleukin 1, beta
ITGA6 integrin, alpha 6
JCHAIN joining chain of multimeric IgA and IgM
LUM lumican
MAGED2 melanoma antigen family D2
MATN2 matrilin 2
MLPH melanophilin
MMP7 matrix metallopeptidase 7
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR1H2 nuclear receptor subfamily 1, group H, member 2
OLFM4 olfactomedin 4
OLFML2A olfactomedin-like 2A
PEG10 paternally expressed 10
PLAU plasminogen activator, urokinase
PTN pleiotrophin
SDC1 syndecan 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SNX7 sorting nexin 7
SYBU syntabulin (syntaxin-interacting)
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TFPI2 tissue factor pathway inhibitor 2
TUBA4A tubulin, alpha 4a
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)