BRD-K18249495_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K18249495_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
CD58 CD58 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
FASN fatty acid synthase
FOS FBJ murine osteosarcoma viral oncogene homolog
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INHBA inhibin, beta A
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUND jun D proto-oncogene
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT81 keratin 81, type II
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PPIF peptidylprolyl isomerase F
S100A2 S100 calcium binding protein A2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SQLE squalene epoxidase
VEGFA vascular endothelial growth factor A
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARHGAP29 Rho GTPase activating protein 29
HOXA10 homeobox A10
HOXB6 homeobox B6
LAMB1 laminin, beta 1
MAOA monoamine oxidase A
MMP2 matrix metallopeptidase 2
NDC80 NDC80 kinetochore complex component
NXN nucleoredoxin
PRIM1 primase, DNA, polypeptide 1 (49kDa)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
WT1 Wilms tumor 1