BRD-K18194590_MEPHENTERMINE SULFATE_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

92 genes differentially expressed following the BRD-K18194590_MEPHENTERMINE SULFATE_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
AQP1 aquaporin 1 (Colton blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C10ORF10 chromosome 10 open reading frame 10
C5AR1 complement component 5a receptor 1
CD200 CD200 molecule
CD300A CD300a molecule
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLIP3 CAP-GLY domain containing linker protein 3
COG7 component of oligomeric golgi complex 7
COL8A2 collagen, type VIII, alpha 2
CPB1 carboxypeptidase B1 (tissue)
CRISP3 cysteine-rich secretory protein 3
CTNND1 catenin (cadherin-associated protein), delta 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
E2F2 E2F transcription factor 2
EIF5A eukaryotic translation initiation factor 5A
ESR1 estrogen receptor 1
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
GCLC glutamate-cysteine ligase, catalytic subunit
GMPR guanosine monophosphate reductase
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOPX HOP homeobox
HOXB2 homeobox B2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
INSM1 insulinoma-associated 1
ITGA8 integrin, alpha 8
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
NEFH neurofilament, heavy polypeptide
PERP PERP, TP53 apoptosis effector
PPAP2B phosphatidic acid phosphatase type 2B
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
QPCT glutaminyl-peptide cyclotransferase
RGS1 regulator of G-protein signaling 1
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SOCS2 suppressor of cytokine signaling 2
ST18 suppression of tumorigenicity 18, zinc finger
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
ARHGAP15 Rho GTPase activating protein 15
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BST2 bone marrow stromal cell antigen 2
C5ORF30 chromosome 5 open reading frame 30
C6ORF48 chromosome 6 open reading frame 48
COL9A3 collagen, type IX, alpha 3
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
GSTM3 glutathione S-transferase mu 3 (brain)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HOXC6 homeobox C6
IL6ST interleukin 6 signal transducer
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
MAB21L2 mab-21-like 2 (C. elegans)
MSRB2 methionine sulfoxide reductase B2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLAC8 placenta-specific 8
PLP1 proteolipid protein 1
RPS27L ribosomal protein S27-like
SACS sacsin molecular chaperone
SKP1 S-phase kinase-associated protein 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
TAC1 tachykinin, precursor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TSPAN3 tetraspanin 3
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble