BRD-K18059238_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K18059238_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ARG2 arginase 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL13 chemokine (C-X-C motif) ligand 13
EIF5A eukaryotic translation initiation factor 5A
GRB7 growth factor receptor-bound protein 7
H2AFV H2A histone family, member V
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
LPAR6 lysophosphatidic acid receptor 6
NELL2 NEL-like 2 (chicken)
OLFM4 olfactomedin 4
ORC1 origin recognition complex, subunit 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SCGB1D2 secretoglobin, family 1D, member 2
STS steroid sulfatase (microsomal), isozyme S
TFPI2 tissue factor pathway inhibitor 2
TRIM2 tripartite motif containing 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
AK1 adenylate kinase 1
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CDK6 cyclin-dependent kinase 6
COCH cochlin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLC1 DLC1 Rho GTPase activating protein
EMP3 epithelial membrane protein 3
F13A1 coagulation factor XIII, A1 polypeptide
FAM107A family with sequence similarity 107, member A
FOLR1 folate receptor 1 (adult)
HSPA2 heat shock 70kDa protein 2
KANK1 KN motif and ankyrin repeat domains 1
LTBP1 latent transforming growth factor beta binding protein 1
NPY neuropeptide Y
PENK proenkephalin
PLTP phospholipid transfer protein
RHOBTB3 Rho-related BTB domain containing 3
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFN stratifin
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)