BRD-K18025010_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

15 genes differentially expressed following the BRD-K18025010_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CHIC2 cysteine-rich hydrophobic domain 2
CLU clusterin
HMOX1 heme oxygenase 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
SPARCL1 SPARC-like 1 (hevin)
SYT1 synaptotagmin I
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CCND1 cyclin D1
CPB1 carboxypeptidase B1 (tissue)
FXYD3 FXYD domain containing ion transport regulator 3
IGFBP3 insulin-like growth factor binding protein 3
LAMB1 laminin, beta 1
NRIP1 nuclear receptor interacting protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)