BRD-K17497770_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K17497770_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANGPT2 angiopoietin 2
ARG2 arginase 2
CD14 CD14 molecule
CD52 CD52 molecule
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRELD2 cysteine-rich with EGF-like domains 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTNND1 catenin (cadherin-associated protein), delta 1
DOCK4 dedicator of cytokinesis 4
DST dystonin
GAREM GRB2 associated, regulator of MAPK1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GIMAP6 GTPase, IMAP family member 6
GNLY granulysin
GRB7 growth factor receptor-bound protein 7
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HOPX HOP homeobox
ICAM2 intercellular adhesion molecule 2
IL7R interleukin 7 receptor
JCHAIN joining chain of multimeric IgA and IgM
LEF1 lymphoid enhancer-binding factor 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOA monoamine oxidase A
MDK midkine (neurite growth-promoting factor 2)
MTF2 metal response element binding transcription factor 2
NELL2 NEL-like 2 (chicken)
NID2 nidogen 2 (osteonidogen)
NOTCH1 notch 1
NOTCH3 notch 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPN3 opsin 3
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPAP2B phosphatidic acid phosphatase type 2B
PPOX protoporphyrinogen oxidase
PPP1R13B protein phosphatase 1, regulatory subunit 13B
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SFRP1 secreted frizzled-related protein 1
TRBC1 T cell receptor beta constant 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSPAN7 tetraspanin 7
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ANXA3 annexin A3
APOE apolipoprotein E
CALD1 caldesmon 1
CCNG2 cyclin G2
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CKB creatine kinase, brain
CRYAB crystallin, alpha B
FLNA filamin A, alpha
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAS1 growth arrest-specific 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
HACD1 3-hydroxyacyl-CoA dehydratase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KRT8 keratin 8, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOX lysyl oxidase
LUM lumican
MAP1B microtubule-associated protein 1B
MAP7 microtubule-associated protein 7
MCL1 myeloid cell leukemia 1
MRPL12 mitochondrial ribosomal protein L12
MTCL1 microtubule crosslinking factor 1
MVP major vault protein
MYL9 myosin, light chain 9, regulatory
PDLIM2 PDZ and LIM domain 2 (mystique)
PLSCR4 phospholipid scramblase 4
PPA1 pyrophosphatase (inorganic) 1
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
SEPP1 selenoprotein P, plasma, 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPM1 tropomyosin 1 (alpha)
UBE2S ubiquitin-conjugating enzyme E2S