BRD-K17497770_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K17497770_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABLIM1 actin binding LIM protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAG3 BCL2-associated athanogene 3
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FOSL1 FOS-like antigen 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HMGA1 high mobility group AT-hook 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
JUN jun proto-oncogene
MAT2A methionine adenosyltransferase II, alpha
NQO1 NAD(P)H dehydrogenase, quinone 1
PGD phosphogluconate dehydrogenase
PHLDA2 pleckstrin homology-like domain, family A, member 2
POPDC3 popeye domain containing 3
RAP1GAP RAP1 GTPase activating protein
SERTAD2 SERTA domain containing 2
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SQSTM1 sequestosome 1
STX1A syntaxin 1A (brain)
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ADA adenosine deaminase
ARMCX1 armadillo repeat containing, X-linked 1
C14ORF132 chromosome 14 open reading frame 132
CTSH cathepsin H
FILIP1L filamin A interacting protein 1-like
GATA2 GATA binding protein 2
GPNMB glycoprotein (transmembrane) nmb
HCAR3 hydroxycarboxylic acid receptor 3
HOPX HOP homeobox
IFI16 interferon, gamma-inducible protein 16
MEIS2 Meis homeobox 2
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
PXDN peroxidasin
RGS5 regulator of G-protein signaling 5
SPON2 spondin 2, extracellular matrix protein
THBS2 thrombospondin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase