BRD-K17075857_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

68 genes differentially expressed following the BRD-K17075857_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ADGRG2 adhesion G protein-coupled receptor G2
AK1 adenylate kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL14A1 collagen, type XIV, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYB5A cytochrome b5 type A (microsomal)
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FTH1 ferritin, heavy polypeptide 1
GCH1 GTP cyclohydrolase 1
GCLM glutamate-cysteine ligase, modifier subunit
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
INSIG1 insulin induced gene 1
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LPAR2 lysophosphatidic acid receptor 2
MAP7 microtubule-associated protein 7
MORC4 MORC family CW-type zinc finger 4
NRG1 neuregulin 1
P3H2 prolyl 3-hydroxylase 2
PAWR PRKC, apoptosis, WT1, regulator
PHGDH phosphoglycerate dehydrogenase
PIR pirin (iron-binding nuclear protein)
PNMA2 paraneoplastic Ma antigen 2
PPAP2C phosphatidic acid phosphatase type 2C
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIK1 salt-inducible kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TRIM16 tripartite motif containing 16
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan
TUSC3 tumor suppressor candidate 3
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
FHL1 four and a half LIM domains 1
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPRC5B G protein-coupled receptor, class C, group 5, member B
GYPC glycophorin C (Gerbich blood group)
IGFBP5 insulin-like growth factor binding protein 5
IGLV2-23 immunoglobulin lambda variable 2-23
MAOA monoamine oxidase A
MPPED2 metallophosphoesterase domain containing 2
NMU neuromedin U
NT5DC2 5'-nucleotidase domain containing 2
RAB31 RAB31, member RAS oncogene family
RGS10 regulator of G-protein signaling 10
SLC26A2 solute carrier family 26 (anion exchanger), member 2
TGFBR3 transforming growth factor, beta receptor III