BRD-K16940042_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K16940042_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASPN asporin
BCL6 B-cell CLL/lymphoma 6
BEX4 brain expressed, X-linked 4
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CECR1 cat eye syndrome chromosome region, candidate 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLGN calmegin
COL11A1 collagen, type XI, alpha 1
CP ceruloplasmin (ferroxidase)
CPE carboxypeptidase E
CST6 cystatin E/M
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DHCR24 24-dehydrocholesterol reductase
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPHA3 EPH receptor A3
FADS1 fatty acid desaturase 1
FBXO21 F-box protein 21
GALC galactosylceramidase
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
KCNK3 potassium channel, two pore domain subfamily K, member 3
LUM lumican
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MYO1D myosin ID
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
PLAU plasminogen activator, urokinase
PODXL podocalyxin-like
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTPRK protein tyrosine phosphatase, receptor type, K
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
SCG5 secretogranin V
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SIK1 salt-inducible kinase 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC38A2 solute carrier family 38, member 2
SQSTM1 sequestosome 1
SULF1 sulfatase 1
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TPPP3 tubulin polymerization-promoting protein family member 3
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
AIM1 absent in melanoma 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CD320 CD320 molecule
CDC25B cell division cycle 25B
COL9A3 collagen, type IX, alpha 3
CRYAB crystallin, alpha B
DMD dystrophin
DSG3 desmoglein 3
F12 coagulation factor XII (Hageman factor)
FCGBP Fc fragment of IgG binding protein
HOXC10 homeobox C10
HOXC6 homeobox C6
KRT15 keratin 15, type I
LOX lysyl oxidase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NRN1 neuritin 1
OPHN1 oligophrenin 1
PARP2 poly (ADP-ribose) polymerase 2
PLAC8 placenta-specific 8
PRR7 proline rich 7 (synaptic)
PTCH1 patched 1
RAD23B RAD23 homolog B (S. cerevisiae)
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SFRP1 secreted frizzled-related protein 1
SMAGP small cell adhesion glycoprotein
SPINK5 serine peptidase inhibitor, Kazal type 5
SPP1 secreted phosphoprotein 1
SPRR3 small proline-rich protein 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFBR3 transforming growth factor, beta receptor III
TNFAIP8 tumor necrosis factor, alpha-induced protein 8