BRD-K16664969_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K16664969_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF5 eukaryotic translation initiation factor 5
FAR2 fatty acyl CoA reductase 2
FZD7 frizzled class receptor 7
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MEIS1 Meis homeobox 1
MTMR11 myotubularin related protein 11
OBSL1 obscurin-like 1
PSAT1 phosphoserine aminotransferase 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TCTA T-cell leukemia translocation altered
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM176B transmembrane protein 176B
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
CA2 carbonic anhydrase II
FGF13 fibroblast growth factor 13
H2AFV H2A histone family, member V
IFI6 interferon, alpha-inducible protein 6
LCN2 lipocalin 2
LTB lymphotoxin beta (TNF superfamily, member 3)
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PRSS23 protease, serine, 23
PXDN peroxidasin
RBM47 RNA binding motif protein 47
RPL37A ribosomal protein L37a
SFRP1 secreted frizzled-related protein 1
SHCBP1 SHC SH2-domain binding protein 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TACC3 transforming, acidic coiled-coil containing protein 3
TF transferrin
TFF1 trefoil factor 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
WSB2 WD repeat and SOCS box containing 2