BRD-K16533489_-666_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K16533489_-666_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT9 acyl-CoA thioesterase 9
ADM adrenomedullin
AKAP8L A kinase (PRKA) anchor protein 8-like
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
CCL2 chemokine (C-C motif) ligand 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRYAB crystallin, alpha B
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
EIF5 eukaryotic translation initiation factor 5
FOSL2 FOS-like antigen 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GREM1 gremlin 1, DAN family BMP antagonist
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
IFI27 interferon, alpha-inducible protein 27
IFRD1 interferon-related developmental regulator 1
IGFBP3 insulin-like growth factor binding protein 3
IL7R interleukin 7 receptor
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
KIAA0753 KIAA0753
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCL1 myeloid cell leukemia 1
MEIS2 Meis homeobox 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP1 matrix metallopeptidase 1
NEBL nebulette
NFIL3 nuclear factor, interleukin 3 regulated
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PALLD palladin, cytoskeletal associated protein
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
SCG5 secretogranin V
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
STC2 stanniocalcin 2
SULF1 sulfatase 1
TFF1 trefoil factor 1
TMPRSS3 transmembrane protease, serine 3
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASRGL1 asparaginase like 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CPVL carboxypeptidase, vitellogenic-like
EPCAM epithelial cell adhesion molecule
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
LAPTM4B lysosomal protein transmembrane 4 beta
LYPLA1 lysophospholipase I
MGP matrix Gla protein
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TM4SF1 transmembrane 4 L six family member 1
TXNIP thioredoxin interacting protein
VCAN versican
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1