BRD-K16485616_mocetinostat_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K16485616_mocetinostat_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD3 abhydrolase domain containing 3
ADM adrenomedullin
AGR2 anterior gradient 2
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C3 aldo-keto reductase family 1, member C3
ALDOC aldolase C, fructose-bisphosphate
APOD apolipoprotein D
CGA glycoprotein hormones, alpha polypeptide
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
EPN2 epsin 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP7 fatty acid binding protein 7, brain
FBLN1 fibulin 1
GPM6A glycoprotein M6A
HMOX1 heme oxygenase 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MMP19 matrix metallopeptidase 19
MNAT1 MNAT CDK-activating kinase assembly factor 1
NFIL3 nuclear factor, interleukin 3 regulated
NRN1 neuritin 1
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PNMA2 paraneoplastic Ma antigen 2
RBP4 retinol binding protein 4, plasma
S100P S100 calcium binding protein P
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
STC1 stanniocalcin 1
SYNGR3 synaptogyrin 3
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMP4 TIMP metallopeptidase inhibitor 4
TNNC1 troponin C type 1 (slow)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSPAN13 tetraspanin 13
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
CA2 carbonic anhydrase II
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COG7 component of oligomeric golgi complex 7
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
GTPBP8 GTP-binding protein 8 (putative)
GUSBP11 glucuronidase, beta pseudogene 11
IGFBP7 insulin-like growth factor binding protein 7
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
JMJD6 jumonji domain containing 6
KCTD12 potassium channel tetramerization domain containing 12
NPEPL1 aminopeptidase-like 1
PBX3 pre-B-cell leukemia homeobox 3
PDLIM1 PDZ and LIM domain 1
PRDX2 peroxiredoxin 2
PRPF4 pre-mRNA processing factor 4
PYCARD PYD and CARD domain containing
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFC2 replication factor C (activator 1) 2, 40kDa
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
SULF1 sulfatase 1