BRD-K16485616_mocetinostat_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K16485616_mocetinostat_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASRGL1 asparaginase like 1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CXCL8 chemokine (C-X-C motif) ligand 8
EDN3 endothelin 3
FABP7 fatty acid binding protein 7, brain
GNAS GNAS complex locus
GREM1 gremlin 1, DAN family BMP antagonist
IER3 immediate early response 3
IL32 interleukin 32
KIF1A kinesin family member 1A
KIF5C kinesin family member 5C
KRT19 keratin 19, type I
LGALS1 lectin, galactoside-binding, soluble, 1
MARCKSL1 MARCKS-like 1
MGP matrix Gla protein
MT1X metallothionein 1X
MXRA7 matrix-remodelling associated 7
NRCAM neuronal cell adhesion molecule
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PIH1D1 PIH1 domain containing 1
PNMA2 paraneoplastic Ma antigen 2
RAB15 RAB15, member RAS oncogene family
RBP1 retinol binding protein 1, cellular
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG5 secretogranin V
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP4 secreted frizzled-related protein 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
THBS2 thrombospondin 2
VAT1 vesicle amine transport 1
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADI1 acireductone dioxygenase 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AGTR1 angiotensin II receptor, type 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
BPHL biphenyl hydrolase-like (serine hydrolase)
CCR7 chemokine (C-C motif) receptor 7
CD36 CD36 molecule (thrombospondin receptor)
CHMP5 charged multivesicular body protein 5
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A6 collagen, type IV, alpha 6
CXCL13 chemokine (C-X-C motif) ligand 13
DENND2D DENN/MADD domain containing 2D
FAM69A family with sequence similarity 69, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KCTD12 potassium channel tetramerization domain containing 12
KIAA0125 KIAA0125
LTF lactotransferrin
MSMB microseminoprotein, beta-
PALLD palladin, cytoskeletal associated protein
SHB Src homology 2 domain containing adaptor protein B
TFF1 trefoil factor 1
TGFBI transforming growth factor, beta-induced, 68kDa
TTN titin
VCP valosin containing protein