BRD-K16485616_mocetinostat_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

93 genes differentially expressed following the BRD-K16485616_mocetinostat_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
AKR1C1 aldo-keto reductase family 1, member C1
ASPN asporin
AXL AXL receptor tyrosine kinase
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHIC2 cysteine-rich hydrophobic domain 2
CLDN10 claudin 10
COBL cordon-bleu WH2 repeat protein
COL1A1 collagen, type I, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
G6PD glucose-6-phosphate dehydrogenase
GREM1 gremlin 1, DAN family BMP antagonist
HLA-DRA major histocompatibility complex, class II, DR alpha
HOOK2 hook microtubule-tethering protein 2
HSPB8 heat shock 22kDa protein 8
IGF1 insulin-like growth factor 1 (somatomedin C)
ITM2A integral membrane protein 2A
LUM lumican
MAP1B microtubule-associated protein 1B
MGLL monoglyceride lipase
MLPH melanophilin
MVP major vault protein
NNMT nicotinamide N-methyltransferase
OLFM1 olfactomedin 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDLIM1 PDZ and LIM domain 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC8 placenta-specific 8
PLEK2 pleckstrin 2
PLS1 plastin 1
PMEPA1 prostate transmembrane protein, androgen induced 1
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
RGS2 regulator of G-protein signaling 2
S100A4 S100 calcium binding protein A4
SCGB2A1 secretoglobin, family 2A, member 1
SDS serine dehydratase
SFN stratifin
SOX9 SRY (sex determining region Y)-box 9
SST somatostatin
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STX1A syntaxin 1A (brain)
TFF1 trefoil factor 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TPMT thiopurine S-methyltransferase
TUBA1A tubulin, alpha 1a
TXNRD1 thioredoxin reductase 1
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
APLP2 amyloid beta (A4) precursor-like protein 2
ARMCX1 armadillo repeat containing, X-linked 1
C2CD5 C2 calcium-dependent domain containing 5
CAST calpastatin
CCND1 cyclin D1
CST3 cystatin C
CSTA cystatin A (stefin A)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERBB3 erb-b2 receptor tyrosine kinase 3
FXYD3 FXYD domain containing ion transport regulator 3
GSTT1 glutathione S-transferase theta 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGFBP7 insulin-like growth factor binding protein 7
JADE2 jade family PHD finger 2
LRRC41 leucine rich repeat containing 41
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MMP9 matrix metallopeptidase 9
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
PLBD1 phospholipase B domain containing 1
PON2 paraoxonase 2
PXDN peroxidasin
RNH1 ribonuclease/angiogenin inhibitor 1
SEPP1 selenoprotein P, plasma, 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TLR4 toll-like receptor 4
TRIM22 tripartite motif containing 22