BRD-K16472144_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K16472144_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ALB albumin
CAV1 caveolin 1, caveolae protein, 22kDa
CX3CL1 chemokine (C-X3-C motif) ligand 1
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
EIF5A eukaryotic translation initiation factor 5A
EPAS1 endothelial PAS domain protein 1
FN1 fibronectin 1
G0S2 G0/G1 switch 2
HCAR3 hydroxycarboxylic acid receptor 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JAG1 jagged 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1X metallothionein 1X
PECAM1 platelet/endothelial cell adhesion molecule 1
PTN pleiotrophin
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SMC1A structural maintenance of chromosomes 1A
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AK1 adenylate kinase 1
CA12 carbonic anhydrase XII
CXCL12 chemokine (C-X-C motif) ligand 12
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FKBP11 FK506 binding protein 11, 19 kDa
GCH1 GTP cyclohydrolase 1
KDM5D lysine (K)-specific demethylase 5D
KIF20A kinesin family member 20A
OAT ornithine aminotransferase
RPS4Y1 ribosomal protein S4, Y-linked 1
RSRP1 arginine/serine-rich protein 1
TMEM14A transmembrane protein 14A
UBE2A ubiquitin-conjugating enzyme E2A
UGCG UDP-glucose ceramide glucosyltransferase