BRD-K15834839_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-K15834839_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL19 chemokine (C-C motif) ligand 19
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CKS2 CDC28 protein kinase regulatory subunit 2
CLU clusterin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ETNK1 ethanolamine kinase 1
FGFR3 fibroblast growth factor receptor 3
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GRIA2 glutamate receptor, ionotropic, AMPA 2
HMOX1 heme oxygenase 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ITM2A integral membrane protein 2A
KRT19 keratin 19, type I
LTF lactotransferrin
MALL mal, T-cell differentiation protein-like
MAP7 microtubule-associated protein 7
MGLL monoglyceride lipase
MSL2 male-specific lethal 2 homolog (Drosophila)
PDZK1 PDZ domain containing 1
PLP1 proteolipid protein 1
PTCH1 patched 1
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RUNX3 runt-related transcription factor 3
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
CDC42 cell division cycle 42
COL1A1 collagen, type I, alpha 1
COL8A2 collagen, type VIII, alpha 2
CTSK cathepsin K
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
KIAA1033 KIAA1033
KIF14 kinesin family member 14
LRRC17 leucine rich repeat containing 17
NRIP1 nuclear receptor interacting protein 1
PLAU plasminogen activator, urokinase
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
S100A10 S100 calcium binding protein A10
S100A6 S100 calcium binding protein A6
SGPP1 sphingosine-1-phosphate phosphatase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SULF1 sulfatase 1
UGCG UDP-glucose ceramide glucosyltransferase
WSB1 WD repeat and SOCS box containing 1
ZNF91 zinc finger protein 91