BRD-K15791587_L-733,060 hydrochloride_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

35 genes differentially expressed following the BRD-K15791587_L-733,060 hydrochloride_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACLY ATP citrate lyase
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
FABP7 fatty acid binding protein 7, brain
FADS2 fatty acid desaturase 2
FDPS farnesyl diphosphate synthase
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MFAP3L microfibrillar-associated protein 3-like
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
QPCT glutaminyl-peptide cyclotransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TBC1D4 TBC1 domain family, member 4
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)

decreased expression

Symbol Name
ADA adenosine deaminase
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ASPN asporin
AUTS2 autism susceptibility candidate 2
CPA3 carboxypeptidase A3 (mast cell)
DUOX2 dual oxidase 2
FABP4 fatty acid binding protein 4, adipocyte
GPRC5A G protein-coupled receptor, class C, group 5, member A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LMO3 LIM domain only 3 (rhombotin-like 2)
MGP matrix Gla protein
MXRA5 matrix-remodelling associated 5
PLAUR plasminogen activator, urokinase receptor
ZIC1 Zic family member 1