BRD-K15791587_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K15791587_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ACLY ATP citrate lyase
AGTR1 angiotensin II receptor, type 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKRD10 ankyrin repeat domain 10
ANXA2 annexin A2
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CLIC4 chloride intracellular channel 4
CLU clusterin
CRABP1 cellular retinoic acid binding protein 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYSL2 dihydropyrimidinase-like 2
DUSP4 dual specificity phosphatase 4
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GBP2 guanylate binding protein 2, interferon-inducible
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IFITM1 interferon induced transmembrane protein 1
IL13RA2 interleukin 13 receptor, alpha 2
IL32 interleukin 32
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MICB MHC class I polypeptide-related sequence B
MMP7 matrix metallopeptidase 7
MYO6 myosin VI
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PELI1 pellino E3 ubiquitin protein ligase 1
QPRT quinolinate phosphoribosyltransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SDCBP syndecan binding protein (syntenin)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
STC2 stanniocalcin 2
TIMP1 TIMP metallopeptidase inhibitor 1
TNNT1 troponin T type 1 (skeletal, slow)
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
GRWD1 glutamate-rich WD repeat containing 1
ITGA6 integrin, alpha 6
MAT2A methionine adenosyltransferase II, alpha
MMP12 matrix metallopeptidase 12
NCAM1 neural cell adhesion molecule 1
NOP56 NOP56 ribonucleoprotein
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RPS5 ribosomal protein S5
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TCTA T-cell leukemia translocation altered
TSEN2 TSEN2 tRNA splicing endonuclease subunit