BRD-K15567136_PAPAVERINE HYDROCHLORIDE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K15567136_PAPAVERINE HYDROCHLORIDE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CCK cholecystokinin
CELF2 CUGBP, Elav-like family member 2
GATA6 GATA binding protein 6
GPM6A glycoprotein M6A
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
KANK1 KN motif and ankyrin repeat domains 1
MME membrane metallo-endopeptidase
OLFM4 olfactomedin 4
PTN pleiotrophin
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SOX9 SRY (sex determining region Y)-box 9
SSBP2 single-stranded DNA binding protein 2
TFPI2 tissue factor pathway inhibitor 2
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CDC20 cell division cycle 20
COL10A1 collagen, type X, alpha 1
FABP4 fatty acid binding protein 4, adipocyte
FXYD3 FXYD domain containing ion transport regulator 3
GCH1 GTP cyclohydrolase 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA8 heat shock 70kDa protein 8
MFAP5 microfibrillar associated protein 5
NAAA N-acylethanolamine acid amidase
POSTN periostin, osteoblast specific factor
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
TAGLN transgelin
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TIMP3 TIMP metallopeptidase inhibitor 3
TMCO1 transmembrane and coiled-coil domains 1