BRD-K15567136_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K15567136_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF3 activating transcription factor 3
BTG3 BTG family, member 3
CCL5 chemokine (C-C motif) ligand 5
CNN1 calponin 1, basic, smooth muscle
DAPK1 death-associated protein kinase 1
DLC1 DLC1 Rho GTPase activating protein
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
FOSL1 FOS-like antigen 1
FUCA1 fucosidase, alpha-L- 1, tissue
GALC galactosylceramidase
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER3 immediate early response 3
KAT6B K(lysine) acetyltransferase 6B
LMO3 LIM domain only 3 (rhombotin-like 2)
LRMP lymphoid-restricted membrane protein
NR4A3 nuclear receptor subfamily 4, group A, member 3
NXN nucleoredoxin
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
POSTN periostin, osteoblast specific factor
RAB4A RAB4A, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RFC5 replication factor C (activator 1) 5, 36.5kDa
RGS1 regulator of G-protein signaling 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMAD3 SMAD family member 3
TIMP3 TIMP metallopeptidase inhibitor 3

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
BEX1 brain expressed, X-linked 1
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
C6ORF62 chromosome 6 open reading frame 62
CDC20 cell division cycle 20
CFB complement factor B
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DPYD dihydropyrimidine dehydrogenase
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FRZB frizzled-related protein
GCH1 GTP cyclohydrolase 1
GPER1 G protein-coupled estrogen receptor 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAGEA3 melanoma antigen family A3
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
NPY1R neuropeptide Y receptor Y1
NUSAP1 nucleolar and spindle associated protein 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDLIM1 PDZ and LIM domain 1
RTN1 reticulon 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STAB1 stabilin 1
SYBU syntabulin (syntaxin-interacting)
TRIM2 tripartite motif containing 2
ZC3H4 zinc finger CCCH-type containing 4