BRD-K15563106_-666_A375_6.0_h_177.6_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K15563106_-666_A375_6.0_h_177.6_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR3 early growth response 3
FILIP1L filamin A interacting protein 1-like
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
H2BFS H2B histone family, member S (pseudogene)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER5 immediate early response 5
LAPTM5 lysosomal protein transmembrane 5
MSLN mesothelin
RGS10 regulator of G-protein signaling 10
RGS2 regulator of G-protein signaling 2
S100P S100 calcium binding protein P

decreased expression

Symbol Name
CCNF cyclin F
DKK1 dickkopf WNT signaling pathway inhibitor 1
HES1 hes family bHLH transcription factor 1
MAP1B microtubule-associated protein 1B
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PFN2 profilin 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase