BRD-K15419449_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K15419449_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
AKAP12 A kinase (PRKA) anchor protein 12
APOD apolipoprotein D
ARMCX2 armadillo repeat containing, X-linked 2
ATF3 activating transcription factor 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BEX4 brain expressed, X-linked 4
BHLHE41 basic helix-loop-helix family, member e41
C10ORF10 chromosome 10 open reading frame 10
DDIT4 DNA-damage-inducible transcript 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FN1 fibronectin 1
FST follistatin
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPM6B glycoprotein M6B
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
IFI27 interferon, alpha-inducible protein 27
IGFBP7 insulin-like growth factor binding protein 7
IGKV4-1 immunoglobulin kappa variable 4-1
KRT6B keratin 6B, type II
LY96 lymphocyte antigen 96
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP9 matrix metallopeptidase 9
PDLIM3 PDZ and LIM domain 3
PLIN2 perilipin 2
PLN phospholamban
PPAP2B phosphatidic acid phosphatase type 2B
RFTN1 raftlin, lipid raft linker 1
RHOB ras homolog family member B
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCG5 secretogranin V
SNAI2 snail family zinc finger 2
THBS2 thrombospondin 2
UPP1 uridine phosphorylase 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD81 CD81 molecule
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
EVL Enah/Vasp-like
HSPH1 heat shock 105kDa/110kDa protein 1
KIF20A kinesin family member 20A
LTBP3 latent transforming growth factor beta binding protein 3
NPDC1 neural proliferation, differentiation and control, 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PIEZO1 piezo-type mechanosensitive ion channel component 1
PRKCD protein kinase C, delta
RNH1 ribonuclease/angiogenin inhibitor 1
SFRP1 secreted frizzled-related protein 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TTC3 tetratricopeptide repeat domain 3
UBE2S ubiquitin-conjugating enzyme E2S